Experimental models are critical to advancing our knowledge on the role of Blastocystis in health and disease.
We have now published our work led by Dr Katerina Pomajbikova on the suitability of the rat as a model of Blastocystis colonisation. We observed that the rats were able to sustain the colonisation for more than one year, when a ST1 strain isolated from a human was used.
Next step could now be to monitor gut microbiota before and after challenge with Blastocystis cysts and look for changes at both individual and community level,, changes in alpha and beta diversity, etc.
The paper is free for download here until August 19, 2018.
We have now published our work led by Dr Katerina Pomajbikova on the suitability of the rat as a model of Blastocystis colonisation. We observed that the rats were able to sustain the colonisation for more than one year, when a ST1 strain isolated from a human was used.
Next step could now be to monitor gut microbiota before and after challenge with Blastocystis cysts and look for changes at both individual and community level,, changes in alpha and beta diversity, etc.
The paper is free for download here until August 19, 2018.
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